[youtube http://www.youtube.com/watch?v=M4p3JI7s1dw]
As part of the Pioneer Session at the 2012 GET Conference, Eric Alm gave an overview of his effort to create a high resolution characterization of the microbial communities in his own gut by collecting and analyzing daily stool samples for a year (video).
I've heard Eric's research endearingly referred to as the "#2-ome"! Lawrence David, a former graduate student in Eric's lab at MIT, also participated in this self-study experiment. He runs an aptly named website: stinkpot.org.